ProtoICH is a computational application for the prediction of mutagenicity of chemical compounds, by using proprietary QSAR models.

ProtoICH is specially focused on ICH M7 Guideline, a European Union regulation, adopted to reduce the potential carcinogenic risk of impurities. ICH M7 Guideline proposes the use of computational methods as an alternative for mutagenicity assays. It requires the prediction by means of two computational metodologies: an statistical method (QSAR) and a expert-rule based method.

ProtoICH KEY FEATURES:

  • Speed: predictions in a few seconds/minutes, even for large sets of molecules (about five minutes for a prediction of 10 properties in a dataset of 1000 molecules).
  • Versatility: different input formats can be provided as inputs.
  • Simplicity: no need of specific or technical knowledge to use the tool.
  • Regulatory validity: all models follow the OECD guidelines and are provided with their corresponding reports following the QSAR Model Reporting Format (QMRF), therefore guaranteeing their use for regulatory purposes.

ON-LINE VERSION: TRIAL HERE

DESKTOP VERSION