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Required REACH endpoints
Annex VII
7. Physicochemical properties
7.1 State of the substance
7.2 Melting/freezing point
7.3 Boiling point
7.4 Relative density
7.5 Vapour pressure
7.6 Surface tension
7.7 Water solubility
7.8 Partition coefficient n-octanol/water
7.9 Flash-point
7.10 Flammability
7.11 Explosive properties
7.12 Self-ignition temperature
7.13 Oxidising properties
7.14 Granulometry
8. Toxicological information
8.1 Skin irritation or skin corrosion (in vitro)
8.2 Eye irritation (in vitro)
8.3 Skin sensitisation
8.4 Mutagenicity (in vitro-gene mutation study in bacteria)
8.5 Acute toxicity (by oral route)
9. Ecotoxicological information
9.1 Aquatic toxicity (short-term toxicity testing on invertebrates)
9.2 Degradation
Annex VIII
8. Toxicological information
8.1.1 Skin irritation (in vivo skin irritation)
8.2.1 Eye irritation (in vivo eye irritation)
8.4.2 Mutagenicity (in vitro cytogenicity study in mammalian cells or in vitro micronucleus study)
8.5.2 and 8.5.3 Acute toxicity (by inhalation, by dermal route)
8.6 Repeated dose toxicity (28 days)
8.7 Reproductive toxicity (screening)
8.8 Toxicokinetics (assessment of relevant available information)
9. Ecotoxicological information
9.1.3 and 9.1.4 Short-term toxicity testing (on fish, activated sludge respiration inhibition testing)
9.2.2.1 Degradation (hydrolysis as a function of pH)
9.3 Fate and behaviour in the environment
Annex IX
7. Physicochemical properties
7.15 Stability in organic solvents and identity of relevant degradation products
7.16 Dissociation constant
7.17 Viscosity
8. Ecotoxicological information
9. Ecotoxicological information
9.1.5 and 9.1.6 Long-term toxicity testing on invertebrates and fish
9.2 Degradation (9.2.1; 9.2.1.2; 9.2.1.3; 9.2.1.4; 9.2.3)
9.3.2 Bioaccumulation in aquatic species
9.3.3 Further information on adsorption/desorption
9.4 Effects on terrestrial organisms (9.4.1 – 9.4.3)
Annex X
8. Ecotoxicological information
8.7 Reproductive toxicity
8.7.2 Developmental toxicity study
8.7.3 Two-generation reproductive toxicity study
8.9.1 Carcinogenicity study
9. Ecotoxicological information
9.2 Degradation
9.3 Fate and behaviour in the environment (9.3.4 included)
9.4 Effects on terrestrial organisms
9.4.4 and 9.4.6 Long-term toxicity testing on invertebrates and plants
9.5.1 Long-term toxicity to sediment organisms
9.6.1 Long-term or reproductive toxicity to birds