The European Regulation No. 1272/2008 known as CLP (from “Classification, Labeling and Packaging”) establishes the classification criteria and labeling rules of substances and mixtures within the EU. The CLP is mandatory for EU companies, which have to appropriately classify label and package their substances and mixtures before placing them on the market. The aim of CLP regulation is to protect workers, consumers and environment by clearly labeling particular chemicals potential hazards.Among the fundamental obligations of CLP, highlights the labeling of chemical products, which must be clearly visible on the packaging, and report the potential hazards of the substances it contains.

The Safety Data Sheets (SDS) are also regulated, which represent a fundamental tool in the field of occupational risk prevention. SDS are a widely used system for cataloging information on chemicals and mixtures, and they include all the required instructions for the safe use and potential risks associated with a particular substance. SDS have to be available in the area where the chemicals are stored or used.

In ProtoQSAR we have specific models related to the CLP regulation, such as flammability, explosive character, ocular toxicity, dermal toxicity, ecotoxicity, etc.