Normative ICH

Normative ICH

What characteristics should a QSAR model have from a regulatory point of view? A case of the ICH regulation. As we saw in our previous post about what QSAR models are and how are they created, the REACH (chemical products) and ICH (drug) legislations not only accept, but also promote the use of alternative methods to animal testing for the evaluation of physicochemical and toxicological properties. Among these alternative methods, as you already know, are computational methods. In this post we are going to explain the requirements that these legislations have for computational models and, more specifically, the (Q)SAR methods. On the one hand, ECHA (European Chemicals Agency) points out […]